Clues to why most survived China melamine scandal

WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.

In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?

A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.

The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.

The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.

A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.

Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.

Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.

More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.

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Wall Street pauses after rally to five-year high

NEW YORK (Reuters) - Stocks drifted in light volume on Wednesday, ending little changed, as investors remained cautious after the S&P 500 index briefly hit its highest intraday level since November 2007.

The S&P 500 was buoyed by General Electric after cable company Comcast Corp said it will buy from GE the the part of NBCUniversal it didn't already own for $16.7 billion.

Comcast's stock hit the highest since 1999 before closing up 3 percent at $40.13 and GE gained 3.6 percent to $23.39.

The S&P 500 is up 6.6 percent so far this year, partly due to stronger-than-expected corporate earnings and a better economic outlook. The Dow industrials is about 1 percent away from an all-time intraday high, reached in October 2007.

Volume has been weak in recent days with the S&P moving sideways around 1,520. The index is about 3 percent away from closing at a record high.

A scarcity of sellers after a consistent string of gains is a positive sign and shows the uptrend is intact, King Lip, chief investment officer at Baker Avenue Asset Management in San Francisco, said.

"Last year we had double-digit returns in the first quarter. It's fairly possible we can move higher from here," he said.

The Dow Jones industrial average <.dji> fell 35.79 points or 0.26 percent, to 13,982.91, the S&P 500 <.spx> gained 0.9 point or 0.06 percent, to 1,520.33 and the Nasdaq Composite <.ixic> added 10.38 points or 0.33 percent, to 3,196.88.

The S&P gained 12 percent in the first three months of 2012.

Deere & Co , the world's largest farm equipment maker, forecast a modest increase in sales this year despite the prospect of the biggest corn crop in U.S. history. The forecast fell short of analysts' expectations, sending shares of Deere down 3.5 percent to $90.68.

In extended trading, shares of technology bellwether Cisco Systems fell 2 percent after it posted results.

Dr Pepper Snapple fell 5.8 percent to $42.69 after it forecast profit for the current year below analysts' estimates.

Cliffs Natural Resources lost a fifth of its market value a day after the miner reported a quarterly loss and slashed its dividend by 76 percent. Its shares fell 20 percent to 429.29.

According to the latest Thomson Reuters data, of the 364 companies in the S&P 500 that have reported results, 70.3 percent have exceeded analysts' expectations, above a 62 percent average since 1994 and 65 percent over the past four quarters.

About 5.9 billion shares changed hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, below the daily average in February last year of 6.94 billion.

On the NYSE, roughly seven issues rose for every five that fell and on Nasdaq more than six rose for every five decliners.

(Editing by Kenneth Barry and Bernadette Baum)

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Despite Claims of Third Blast, North Korean Nuclear Program Remains a Mystery

As scientists and world leaders scrambled Tuesday to judge the importance of North Korea’s claim that it had detonated a third nuclear bomb, the main thing that quickly became evident is how little is known about the country’s increasingly advanced atomic and missile programs.

Even the best news about the test — that it was small by world standards — could have a dangerous downside if the North’s statement that it is learning to miniaturize bombs is true. That technology, which is extremely difficult to master, is crucial to being able to load a weapon atop a long-range missile that might one day reach as far as the United States mainland.

“We don’t know enough to nail it, but we can’t rule out that they’ve done something dangerous” Ray E. Kidder, a scientist who pioneered early nuclear warhead designs at the Livermore weapons lab in California, said of the underground test.

As is usual with tests by the secretive North, it was not even clear if the underground test was nuclear, rather than conventional bomb blasts meant to mimic an underground nuclear test. Experts assume it was nuclear partly from the shape of its seismic signal and because the blast was at the same mountainous site as two earlier nuclear tests.

It also remains unclear whether the North used plutonium or enriched uranium to fuel the bomb. American officials believed that the country’s last two nuclear tests, in 2006 and 2009, used plutonium, and they fear a switch to uranium will allow the country a faster and harder-to-detect path to a bigger arsenal. While scientists are actively hunting for the airborne markers of a uranium test, it is not certain that gases needed to make that judgment escaped the test site.

Scientists said the relatively small size of Tuesday’s blast calmed, at least temporarily, their worst fears: that the North’s recent references to more powerful hydrogen bombs indicated the possibility that it might have at least enough technology to try to test one. Those bombs, nicknamed city-busters, are roughly 1,000 times stronger than atom bombs, and if the North were to get them it would represent an enormous leap in its known abilities. The first American hydrogen bomb to be tested caused the Pacific island of Elugelab to vanish.

What emerged most clearly Tuesday from sensitive global networks that measure faint rumbles in the earth was that the underground blast was most likely larger than North Korea’s past explosions. In Vienna, the preparatory commission for the Comprehensive Nuclear Test Ban Treaty Organization, which runs a global seismic network, said the blast measured 5.0 in seismic magnitude. The United States Geological Survey put its own estimate at 5.1 in magnitude.

Nuclear experts said the magnitude of the blast equaled an atomic blast of about 6,000 tons of high explosive, or six kilotons. The first test by Pyongyang is thought to have packed less than a kiloton of power and was considered a partial failure by the West. The state’s 2009 blast was judged by American intelligence officials to have a power of two kilotons, though some experts outside the government say it might have been as large as this week’s test.

In any case, said Paul Richards, a seismologist at Columbia University’s Lamont-Doherty Earth Observatory in Palisades, N.Y., it was “a serious explosion.”

Still, even the largest estimates are small by world standards. The first three nuclear tests of China, for instance, were measured at 22 kilotons, 35 kilotons and 250 kilotons.

North Korea’s tests “are limited in explosive power compared with most previous ones,” said Robert S. Norris, a senior fellow at the Federation of American Scientists in Washington, and the author of “Racing for the Bomb,” a biography of Gen. Leslie R. Groves, the Manhattan Project’s military leader. Determining whether the test was fueled by plutonium or uranium is critical because North Korea in 2007 shut down its reactor that made plutonium, prompting analysts to conclude that its supplies of the rare element are now running low. Intelligence officials estimated it had enough fuel for 6 to 10 bombs.

But in 2010, the state revealed what appears to be a fairly advanced program to enrich uranium, which in theory could fuel many bombs since experts believe that North Korea has rich uranium deposits.

Siegfried S. Hecker, a former director of the Los Alamos weapons lab in New Mexico who has repeatedly visited North Korea and learned details of Pyongyang’s nuclear program, has suggested that North Korea may be ready to switch to a pure uranium approach, in part because it might have a blueprint for a miniaturized uranium warhead.

He said the North’s leadership might have obtained the blueprint from A. Q. Khan, the rogue Pakistani nuclear expert, a blueprint of the type he gave Libya for a uranium bomb. It is well known that North Korea obtained its centrifuge design for uranium enrichment from Dr. Khan, and many experts say the Pakistani expert may have thrown in the warhead blueprint as a sweetener.

Analysts say the uranium approach may also offer North Korea the allure of a new secrecy. Centrifuge plants are much easier to hide than reactors.

Finding out whether the bomb was fueled by plutonium, uranium or a mix of the two materials could take some time or might never happen, analysts say.

Not all underground tests leak their explosive residues into the atmosphere or surrounding waters, and some say tests of the size of Tuesday’s blast are probably strong enough to seal any cracks in the rocks.

“If we get samples, I’m sure we’ll learn a lot about it,” Jay C. Davis, a nuclear scientist who helped found a federal effort to improve such analyses, said in an interview.

But if no bomb residue leaks, he added, the nature of the fuel that North Korean used for its third blast may remain a mystery.

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Larry Bird's Son Connor Arrested

02/12/2013 at 10:00 PM EST

Conner Bird

Monroe County Sheriff’s Office/AP

Basketball star Larry Bird's son is in trouble with the law.

According to CBS Chicago, 21-year-old Connor Bird was involved in an argument with an ex-girlfriend at his apartment on Sunday afternoon and reportedly threw a cell phone at her.

Hours later, the two drove to a nearby parking lot where the woman got out of the car, intending to walk home, and Conner allegedly attempted to hit her twice with his vehicle.

Bird was later arrested by the Indiana University Police on charges of battery with injury, criminal mischief, intimidation with a deadly weapon and possession of marijuana. He is now free on bail. No trial date has been set.

A lawyer for Bird tells PEOPLE: "What has happened is a very private matter. We’re trying to resolve this as quickly as possible and we're all thankful no one was seriously injured."

Bird was reportedly arrested in 2011 for underage drinking and disorderly conduct, according to TMZ.

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Study questions kidney cancer treatment in elderly

In a stunning example of when treatment might be worse than the disease, a large review of Medicare records finds that older people with small kidney tumors were much less likely to die over the next five years if doctors monitored them instead of operating right away.

Even though nearly all of these tumors turned out to be cancer, they rarely proved fatal. And surgery roughly doubled patients' risk of developing heart problems or dying of other causes, doctors found.

After five years, 24 percent of those who had surgery had died, compared to only 13 percent of those who chose monitoring. Just 3 percent of people in each group died of kidney cancer.

The study only involved people 66 and older, but half of all kidney cancers occur in this age group. Younger people with longer life expectancies should still be offered surgery, doctors stressed.

The study also was observational — not an experiment where some people were given surgery and others were monitored, so it cannot prove which approach is best. Yet it offers a real-world look at how more than 7,000 Medicare patients with kidney tumors fared. Surgery is the standard treatment now.

"I think it should change care" and that older patients should be told "that they don't necessarily need to have the kidney tumor removed," said Dr. William Huang of New York University Langone Medical Center. "If the treatment doesn't improve cancer outcomes, then we should consider leaving them alone."

He led the study and will give results at a medical meeting in Orlando, Fla., later this week. The research was discussed Tuesday in a telephone news conference sponsored by the American Society of Clinical Oncology and two other cancer groups.

In the United States, about 65,000 new cases of kidney cancer and 13,700 deaths from the disease are expected this year. Two-thirds of cases are diagnosed at the local stage, when five-year survival is more than 90 percent.

However, most kidney tumors these days are found not because they cause symptoms, but are spotted by accident when people are having an X-ray or other imaging test for something else, like back trouble or chest pain.

Cancer experts increasingly question the need to treat certain slow-growing cancers that are not causing symptoms — prostate cancer in particular. Researchers wanted to know how life-threatening small kidney tumors were, especially in older people most likely to suffer complications from surgery.

They used federal cancer registries and Medicare records from 2000 to 2007 to find 8,317 people 66 and older with kidney tumors less than 1.5 inches wide.

Cancer was confirmed in 7,148 of them. About three-quarters of them had surgery and the rest chose to be monitored with periodic imaging tests.

After five years, 1,536 had died, including 191 of kidney cancer. For every 100 patients who chose monitoring, 11 more were alive at the five-year mark compared to the surgery group. Only 6 percent of those who chose monitoring eventually had surgery.

Furthermore, 27 percent of the surgery group but only 13 percent of the monitoring group developed a cardiovascular problem such as a heart attack, heart disease or stroke. These problems were more likely if doctors removed the entire kidney instead of just a part of it.

The results may help doctors persuade more patients to give monitoring a chance, said a cancer specialist with no role in the research, Dr. Bruce Roth of Washington University in St. Louis.

Some patients with any abnormality "can't sleep at night until something's done about it," he said. Doctors need to say, "We're not sticking our head in the sand, we're going to follow this" and can operate if it gets worse.

One of Huang's patients — 81-year-old Rhona Landorf, who lives in New York City — needed little persuasion.

"I was very happy not to have to be operated on," she said. "He said it's very slow growing and that having an operation would be worse for me than the cancer."

Landorf said her father had been a doctor, and she trusts her doctors' advice. Does she think about her tumor? "Not at all," she said.

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Online:

Kidney cancer info: http://www.cancer.net/cancer-types/kidney-cancer

and http://www.cancer.gov/cancertopics/types/kidney

Study: http://gucasym.org

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Comcast to buy rest of NBC stake for $16.7 billion

(Reuters) - Comcast Corp on Tuesday said it would buy General Electric's remaining 49 percent equity stake in their NBCUniversal joint venture for about $16.7 billion, speeding up a deal that had not been expected until at least late 2014.

Analysts said Comcast was getting a good deal at that price, while Comcast's chief executive said the company moved because it was eager to take control of the business sooner than planned.

Comcast shares rose 7.5 percent in afterhours trading.

Comcast bought 51 percent of NBC Universal in 2011 after winning antitrust approval from the Justice Department. The transaction created a $30 billion business that includes broadcast, cable networks, movie studios and theme parks.

"Pretty much in our opinion given that media stocks have gone up quite a bit, it's a very attractive price, a fair price because we had a formula buyout," Comcast Chairman and Chief Executive Brian Roberts said in an interview with Reuters. "We feel many good things coming today and in the future and we wanted to get 100 percent of that for our shareholders."

In addition to the main deal, NBCUniversal will also buy from GE Capital the properties it uses at 30 Rockefeller Plaza in New York City and CNBC's headquarters in Englewood Cliffs, New Jersey, for about $1.4 billion.

Comcast said it would fund the deal with $11.4 billion of cash on hand, $4 billion in senior unsecured notes to be issued to GE, $2 billion in credit facility borrowings and the issuance of $725 million in subsidiary preferred stock to GE.

Separately, Comcast said it would increase its dividend by 20 percent and that it would buy back $2 billion in stock this year. GE also said it would accelerate its own share buy-back program to $10 billion this year.

"It's an attractive price - Comcast is getting a good deal," Wunderlich Securities analyst Matthew Harrigan said.

LONG-HELD AMBITIONS

Comcast turned its attention to NBC after a failed $54 billion hostile takeover attempt of Disney in 2004 that ultimately led to the resignation of that company's CEO, Michael Eisner, after more than 20 years on the job.

The hostile offer exposed Comcast's desire to merge content with distribution at a time when most of its industry peers, such as Viacom-CBS and AOL-Time Warner, were doing the opposite.

While Comcast held the title of the nation's leading cable operator by a wide margin, its status as a content player was always second tier, with middling networks like E!, G4 and Golf forming the basis of its channel portfolio.

The NBC deal gave the Philadelphia-based cable operator the cable industry's top-rated entertainment network, USA, its leading business network CNBC, upstart news network MSNBC and Bravo, among others.

For GE, the sale culminates a long-planned exit from the entertainment business.

Since reaching the deal to sell its majority stake in NBC Universal, GE officials have made clear that they eventually planned to exit the entertainment business entirely.

The initial sale contract gave GE the option to sell back as much as all its remaining stake in NBC Universal by mid-2014.

The company's accelerated share buyback could be an answer to shareholders, who have wondered what GE would do with a cash windfall that could total tens of billions of dollars over several years, as the company sold its remaining NBC stake and recouped more profits earned by GE Capital.

COMCAST EARNINGS

In addition to the GE deal, Comcast reported fourth-quarter earnings on Tuesday.

It posted $15.94 billion in revenue, up 6 percent from a year ago. It posted net income of $1.8 billion, or 56 cents per share, up from $1.56 billion, or 47 cents a year ago.

In its cable business, it lost a net 7,000 video customers, which is better than the 17,000 subscribers lost a year ago.

Wall Street analysts were expecting Comcast to lose 5,000 customers, according to StreetAccount. It added 341,000 Internet customers in the quarter, which beat the 329,000 new customers analysts were expecting.

Comcast shares rose to $41.89 after the market close from $38.97 in regular trading. GE shares rose 3 percent to $23.37 from a $22.58 close.

(Reporting by Liana B. Baker, Jennifer Saba and Peter Lauria in New York, Diane Bartz in Washington, Scott Malone in Boston and A. Ananthalakshmi in Bangalore; Writing by Ben Berkowitz; Editing by Dan Grebler)

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North Korea Promises to Test More Rockets

SEOUL, South Korea — The Politburo of North Korea’s ruling Workers’ Party has called for the continued testing of long-range rockets despite the condemnation of previous tests by the United Nations Security Council, the country’s official media reported Tuesday.

In a meeting on Monday, the Politburo, the main decision-making body of the party, said that more rocket tests could be an appropriate way to celebrate the 65th anniversary of North Korea’s founding and the 60th anniversary of the end of the Korean War.

North Korea declared itself as an independent state on Sept. 9, 1948, three years after the liberation of the Korean Peninsula from Japanese colonial rule. It also marks July 27, the day when the truce was signed 60 years ago to end the Korean War. North Korea celebrates those dates each year with hostile statements directed at countries it considers its enemies, as well as with festivities aimed at increasing domestic support for its top leaders.

The Monday meeting was the first time the Politburo had convened since July 2012, when it decided to dismiss Ri Yong-ho, a senior army general. That dismissal turned out to be the beginning of a round of political purges under the new supreme leader, Kim Jong-un.

The 10-point decision adopted at the meeting on Monday called for a huge military parade in Pyongyang, the capital, to mark the anniversary of the July 27 truce, as well as the construction of an international tourism complex in Wonsan, a port on the central eastern coast of North Korea. The Politburo also called for South Korea to fulfill promises to make large investments in the North, which were part of agreements reached in 2000 and 2007.

But the statement did not mention the nuclear test that North Korea has recently threatened to carry out. Officials in South Korea say that enough preparations have been made at a nuclear test site in northeastern North Korea that a test could happen at any time.

The Politburo decision “stressed continuing to launch Kwangmyongsong-class satellites and powerful long-range rockets,” the North’s official Korean Central News Agency reported in its Tuesday dispatch, adding that North Korea should mark the two anniversaries this year with “new achievements for strengthening national defense.”

North Korea launched a rocket on Dec. 12, putting its Kwangmyongsong-3 satellite into orbit, the first for the impoverished country. Washington and its allies said that the rocket launching was a cover for North Korea to develop intercontinental ballistic missiles that could reach North America. The Security Council condemned the launching as a violation of its earlier resolutions that banned the North from testing technology used for ballistic missiles, and last month it adopted another resolution ordering the tightening of sanctions against North Korea.

North Korea has since issued a series of statements threatening more rocket and nuclear tests. The country conducted an underground nuclear test in 2006 and again in 2009.

The Politburo is the center of power in the Workers’ Party. Its Presidium consists of Mr. Kim, who is the top party secretary, and other leaders loyal to him.

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It's a Girl for John Cho

Mom & Babies
Celebrity Baby Blog

02/11/2013 at 06:30 PM ET

Paul Drinkwater/NBC

Surprise: Actor John Cho is a dad again!

The Go On star and his wife welcomed a daughter recently, Cho’s rep confirms to PEOPLE exclusively.

Baby girl is the second child for the couple, who are also parents to a son. No further details are available.

Cho currently stars alongside Jason Bateman in Identity Thief and will reprise his role as Hikaru Sulu in Star Trek Into Darkness in May.

He is also well known for his roles in American Pie and the Harold and Kumar films.

– Anya Leon with reporting by Julie Jordan

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Pope shows lifetime jobs aren't always for life

The world seems surprised that an 85-year-old globe-trotting pope who just started tweeting wants to resign, but should it be? Maybe what should be surprising is that more leaders his age do not, considering the toll aging takes on bodies and minds amid a culture of constant communication and change.

There may be more behind the story of why Pope Benedict XVI decided to leave a job normally held for life. But the pontiff made it about age. He said the job called for "both strength of mind and body" and said his was deteriorating. He spoke of "today's world, subject to so many rapid changes," implying a difficulty keeping up despite his recent debut on Twitter.

"This seemed to me a very brave, courageous decision," especially because older people often don't recognize their own decline, said Dr. Seth Landefeld, an expert on aging and chairman of medicine at the University of Alabama at Birmingham.

Age has driven many leaders from jobs that used to be for life — Supreme Court justices, monarchs and other heads of state. As lifetimes expand, the woes of old age are catching up with more in seats of power. Some are choosing to step down rather than suffer long declines and disabilities as the pope's last predecessor did.

Since 1955, only one U.S. Supreme Court justice — Chief Justice William Rehnquist — has died in office. Twenty-one others chose to retire, the most recent being John Paul Stevens, who stepped down in 2010 at age 90.

When Thurgood Marshall stepped down in 1991 at the age of 82, citing health reasons, the Supreme Court justice's answer was blunt: "What's wrong with me? I'm old. I'm getting old and falling apart."

One in 5 U.S. senators is 70 or older, and some have retired rather than seek new terms, such as Hawaii's Daniel Akaka, who left office in January at age 88.

The Netherlands' Queen Beatrix, who just turned 75, recently said she will pass the crown to a son and put the country "in the hands of a new generation."

In Germany, where the pope was born, Chancellor Angela Merkel, who is 58, said the pope's decision that he was no longer fit for the job "earns my very highest respect."

"In our time of ever-lengthening life, many people will be able to understand how the pope as well has to deal with the burdens of aging," she told reporters in Berlin.

Experts on aging agreed.

"People's mental capacities in their 80s and 90s aren't what they were in their 40s and 50s. Their short-term memory is often not as good, their ability to think quickly on their feet, to execute decisions is often not as good," Landefeld said. Change is tougher to handle with age, and leaders like popes and presidents face "extraordinary demands that would tax anybody's physical and mental stamina."

Dr. Barbara Messinger-Rapport, geriatrics chief at the Cleveland Clinic, noted that half of people 85 and older in developed countries have some dementia, usually Alzheimer's. Even without such a disease, "it takes longer to make decisions, it takes longer to learn new things," she said.

But that's far from universal, said Dr. Thomas Perls, an expert on aging at Boston University and director of the New England Centenarians Study.

"Usually a man who is entirely healthy in his early 80s has demonstrated his survival prowess" and can live much longer, he said. People of privilege have better odds because they have access to good food and health care, and tend to lead clean lives.

"Even in the 1500s and 1600s there were popes in their 80s. It's remarkable. That would be today's centenarians," Perls said.

Arizona Sen. John McCain turned 71 while running for president in 2007. Had he won, he would have been the oldest person elected to a first term as president. Ronald Reagan was days away from turning 70 when he started his first term as president in 1981; he won re-election in 1984. Vice President Joe Biden just turned 70.

In the U.S. Senate, where seniority is rewarded and revered, South Carolina's Strom Thurmond didn't retire until age 100 in 2002. Sen. Robert Byrd of West Virginia was the longest-serving senator when he died in office at 92 in 2010.

Now the oldest U.S. senator is 89-year-old Frank Lautenberg of New Jersey. The oldest congressman is Ralph Hall of Texas who turns 90 in May.

The legendary Alan Greenspan was about to turn 80 when he retired as chairman of the Federal Reserve in 2006; he still works as a consultant.

Elsewhere around the world, Cuba's Fidel Castro — one of the world's longest serving heads of state — stepped down in 2006 at age 79 due to an intestinal illness that nearly killed him, handing power to his younger brother Raul. But the island is an example of aged leaders pushing on well into their dotage. Raul Castro now is 81 and his two top lieutenants are also octogenarians. Later this month, he is expected to be named to a new, five-year term as president.

Other leaders who are still working:

—England's Queen Elizabeth, 86.

—Abdullah bin Abd al-Aziz al-Saud, king of Saudi Arabia, 88.

—Sabah al-Ahmad al-Jaber al-Sabah, emir of Kuwait, 83.

—Ruth Bader Ginsburg, U.S. Supreme Court associate justice, 79.

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Associated Press writers Paul Haven in Havana, Cuba; David Rising in Berlin; Seth Borenstein, Mark Sherman and Matt Yancey in Washington, and researcher Judy Ausuebel in New York contributed to this report.

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Yen near fresh lows versus dollar, Asian shares steady

TOKYO (Reuters) - The yen hovered near fresh lows against the dollar and Tokyo stocks jumped back near a 33-month high on Tuesday after markets took comments from a U.S. official as giving Japan the green light to pursue policies that weaken the yen as long as they help beat deflation.

Asian shares were steady, with many regional bourses shut for holidays. Encouraging trade data from China late last week was lending support but non-Japan markets lacked momentum as investors awaited key events such as the U.S. president's State of the Union address for trading cues.

While Japan has faced some criticism from German and other European officials that it is intentionally trying to weaken the yen with monetary easing, rhetoric about a so-called currency war was dialled back ahead of a Group of 20 meeting in Moscow on Friday and Saturday.

U.S. Treasury Undersecretary Lael Brainard said on Monday the United States supports Japanese efforts to end deflation. But she also mentioned that the G7 has long committed to exchange rates determined by market forces, "except in rare circumstances where excess volatility or disorderly movements might warrant cooperation.

European Central Bank council member Jens Weidmann also said the euro was not overvalued at current levels.

The dollar was trading at 94.22 yen after marking on Monday its highest level since May 2010 of 94.465. The euro was trading at 126.28 yen after the yen fell 2 percent against the euro on Monday, pushing it back towards 127.71 yen hit last week, its highest level since April 2010.

"I think the yen's weakening is a function of (playing)catch-up," and not Japan resorting to deliberate devaluation of its currency, said Andrew Wilkinson, chief economic strategist at Miller Tabak & Co. in New York.

"It's the market's way of saying: we're convinced there is a movement afoot to reinflate Japan."

The weaker yen in turn helped bolster sentiment for Japanese stocks, sending the Nikkei average <.n225> 2.6 percent higher. <.t/>

"While currency moves have been sensitive to officials' comments in general, people thought any comment from the G20 would trigger yen buying," said Hiroichi Nishi, an assistant general manager at SMBC Nikko Securities.

"But such worries are receding as she (Brainard) said she supports Japan's efforts to end deflation."

The yen is expected to stay under pressure on expectations that Prime Minister Shinzo Abe will endorse a far more dovish Bank of Japan regime when the current leadership's term ends next month. The BOJ is expected to refrain from taking fresh easing steps when it meets this week.

The MSCI's broadest index of Asia-Pacific shares outside Japan <.miapj0000pus> was little changed. Australian shares inched up 0.1 percent led by financials, as investors waited for corporate earnings results.

Trading resumed in Japan and South Korea but markets remained closed in Singapore, Hong Kong, mainland China, Malaysia and Taiwan.

G20 officials said on Monday the Group of Seven nations are considering a statement this week reaffirming their commitment to "market-determined" exchange rates.

Currency and equities markets were also looking ahead to President Barack Obama's State of the Union address later on Tuesday, for any signs of a deal to avert automatic spending cuts due to take effect on March 1.

"We believe that the G20's take on currency wars, Mr. Obama's upcoming state of the union address, and data on the current condition of the US economy should help markets assess where the global recovery stands and where we are heading," Barclays Capital said in a research report.

Wall Street and world equity markets were little changed in light volume on Monday as a lack of major economic news gave investors little incentive to push prices higher after a robust performance last week.

U.S. and Chinese data last week lifted the tech-focused Nasdaq Composite Index <.ixic> to a 12-year closing high and the Standard & Poor's 500 Index <.spx> to a five-year peak on Friday.

U.S. crude futures edged down 0.2 percent to $96.88 a barrel while Brent steadied around $118.12.

Spot gold stayed near a one-month low.

(Additional reporting by Ayai Tomisawa and Lisa Twaronite in Tokyo; Editing by Edwina Gibbs)

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